CXCR2 antibody

Catalog No. ABIN2470516

Product Details anti-CXCR2 Antibody

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: Protein G Column

Immunogen: IL - 8 Receptor B monoclonal antibody was raised against L1.2 cells expressing IL - 8 Receptor B (Human).

Isotype: IgG1

Application Details

Application Notes: IL-8 Receptor B antibody can be used in immunohistochemistry starting at 5 μg/mL, immunohistochemistry in frozen tissues starting at 1:10 - 1:20, and flow cytometry.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store IL-8 Receptor B antibody at 4 °C or -20 °C.

Target Details for CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Abstract: CXCR2 Products

Synonyms: CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody

Background: Flow Cytometry Recognizes human IL-8 receptor, type B.The IL8RB is a Chemokine Receptor also known as type 1 interleukin-8 receptor. There are three interleukin-8 receptors on chromosome 2: IL8RA (type 2), IL8RB (type 1), and a pseudogene. Results from mouse knock-out studies suggest that IL8RB may inhibit the expansion and development of neutrophils and B cells (Cacalano et al., 1994). IL8RB is a high-affinity receptor for IL8, and for GROalpha, beta, and gamma (Ahuja and Murphy, 1996).

Gene ID: 3579

UniProt: P25025

Pathways: cAMP Metabolic Process