CRP antibody

Catalog No. ABIN2477771

Product Details anti-CRP Antibody

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CRP antibody is un-conjugated

Application: ELISA, Immunodiffusion (ID)

Specificity: This antibody is specific for human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation. In addition to binding to phosphocholine residues, CRP can bind to other autologous and extrinsic ligands on targets, including damaged cell membranes, ribonucleoprotein particles, apoptotic cells and constituents of micro-organisms, and may activate the classical complement pathway through C1q recognition, making CRP a factor in a variety of host defense mechanisms. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD).

Characteristics: Purified IgG

Purification: Purified

Immunogen: Native

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

References for anti-CRP antibody (ABIN2477771)

Pepys, Hirschfield: "C-reactive protein: a critical update." in: The Journal of clinical investigation, Vol. 111, Issue 12, pp. 1805-12, (2003) (PubMed).

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: C-REACTIVE PROTEIN (CRP Products)

Synonyms: PTX1 antibody, crp antibody, AI255847 antibody, Aa1249 antibody, Ab1-341 antibody, Ab2-196 antibody, Ac1-114 antibody, Ac1262 antibody, Ac2-069 antibody, Ba2-693 antibody, APCS antibody, 0610010I23Rik antibody, AW743261 antibody, C77570 antibody, CRP2 antibody, CRP4 antibody, Crp antibody, ESP1 antibody, Hlp antibody, CRP5.1 antibody, zgc:152809 antibody, C-reactive protein antibody, C-reactive protein, pentraxin-related antibody, c-reactive protein, pentraxin-related antibody, cysteine rich protein 2 antibody, CRP antibody, crp antibody, Crp antibody, Crip2 antibody, LOC776376 antibody

Background: Synonyms: CRP

Gene ID: 1401

UniProt: P02741

Pathways: Carbohydrate Homeostasis