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CD32/CD16 antibody

CD32/CD16 Reactivity: Mouse FACS, IP, IF, Func Host: Rat Monoclonal 2-4G2 unconjugated
Catalog No. ABIN2567271
  • Target See all CD32/CD16 products
    CD32/CD16
    Reactivity
    Mouse
    Host
    • 44
    • 1
    • 1
    Rat
    Clonality
    • 41
    • 1
    • 1
    Monoclonal
    Conjugate
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD32/CD16 antibody is un-conjugated
    Application
    • 45
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)
    Specificity
    The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc γ III) and CD 32 (Fc γ II).
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Clone
    2-4G2
    Isotype
    IgG2b
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    CD32/CD16
    Alternative Name
    CD16/CD32 (CD32/CD16 Products)
    Background
    The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc γ III) and CD 32 (Fc γ II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc γ I receptor.
    Gene ID
    14131, 14130
    UniProt
    P08508, P08101
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