CD3 antibody (PerCP-Cy5.5)
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- Target See all CD3 Antibodies
- CD3
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD3 antibody is conjugated to PerCP-Cy5.5
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Application
- Flow Cytometry (FACS)
- Specificity
- The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Clone
- UCHT1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- CD3
- Alternative Name
- CD3 (CD3 Products)
- Synonyms
- CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
- Background
- The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
- Gene ID
- 916
- UniProt
- P07766
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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