CD3 epsilon antibody
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- Target See all CD3 epsilon (CD3E) Antibodies
- CD3 epsilon (CD3E)
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Reactivity
- Mouse
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Host
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Hamster
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Clonality
- Monoclonal
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Conjugate
- This CD3 epsilon antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)
- Specificity
- The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Clone
- 145-2C11
- Isotype
- IgG
- Top Product
- Discover our top product CD3E Primary Antibody
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anti-CD3 epsilon (CD3E) antibody
CD3E Reactivity: Human FACS, WB, IHC Host: Rabbit Monoclonal ARC51750 unconjugated
anti-CD3 epsilon (CD3E) (AA 23-207) antibodyCD3E Reactivity: Human, Mouse, Rat WB, IHC (fro), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (C-Term) antibodyCD3E Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-CD3 epsilon (CD3E) antibodyCD3E Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-CD3 epsilon (CD3E) antibodyCD3E Reactivity: Human, Mouse, Rat FACS, IF, Func Host: Mouse Monoclonal RIV9 unconjugated
anti-CD3 epsilon (CD3E) (AA 23-119) antibodyCD3E Reactivity: Human FACS, WB, IHC, ELISA, Coat, StM Host: Mouse Monoclonal C3e-1931 unconjugated
anti-CD3 epsilon (CD3E) (AA 156-168), (Cytoplasmic Domain) antibodyCD3E Reactivity: Human, Rat, Pig, Rabbit, Cow, Horse, Guinea Pig, Chicken FACS, WB, IF Host: Mouse Monoclonal PC3-188A unconjugated
anti-CD3 epsilon (CD3E) (C-Term) antibodyCD3E Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (AA 25-207) antibodyCD3E Reactivity: Human WB, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-CD3 epsilon (CD3E) (AA 28-185) antibodyCD3E Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- CD3 epsilon (CD3E)
- Alternative Name
- CD3e (CD3E Products)
- Synonyms
- cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody
- Background
- The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
- Gene ID
- 12501
- UniProt
- P22646
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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