CD90.2 / Thy-1.2 antibody (violetFluor™ 450)

Catalog No. ABIN2568052

Product Details anti-CD90.2 / Thy-1.2 Antibody (violetFluor™ 450)

Target: CD90.2 / Thy-1.2

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD90.2 / Thy-1.2 antibody is conjugated to violetFluor™ 450

Application: Flow Cytometry (FACS)

Specificity: The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone: 30-H12

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for CD90.2 / Thy-1.2

Target: CD90.2 / Thy-1.2

Alternative Name: CD90.2 (CD90.2 / Thy-1.2 Products)

Synonyms: CD90 antibody, T25 antibody, Thy-1 antibody, Thy-1.2 antibody, Thy1.1 antibody, Thy1.2 antibody, thymus cell antigen 1, theta antibody, Thy1 antibody

Background: The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma. The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Gene ID: 21838

UniProt: P01831