LRRC8A antibody
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- Target See all LRRC8A Antibodies
- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LRRC8A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- LRRC8A antibody is human, mouse and rat reactive.
- Purification
- LRRC8A antibody is affinity chromatography purified via peptide column.
- Immunogen
- LRRC8A antibody was raised against a 15 amino acid peptide near the amino terminus of human LRRC8A.
- Isotype
- IgG
- Top Product
- Discover our top product LRRC8A Primary Antibody
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- Application Notes
- LRRC8A antibody can be used for detection of LRRC8A by Western blot at 1 - 2 μ,g/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- LRRC8A antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- LRRC8A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
- Alternative Name
- LRRC8A (LRRC8A Products)
- Synonyms
- AGM5 antibody, LRRC8 antibody, Lrrc8 antibody, mKIAA1437 antibody, wu:fb18g12 antibody, wu:fi21b10 antibody, LLRC8A antibody, leucine rich repeat containing 8 VRAC subunit A antibody, leucine rich repeat containing 8A antibody, leucine rich repeat containing 8 VRAC subunit Aa antibody, leucine-rich repeat containing 8 family member A S homeolog antibody, leucine rich repeat containing 8 family member A antibody, LRRC8A antibody, Lrrc8a antibody, lrrc8aa antibody, lrrc8a.S antibody
- Background
- The leucine rich repeat containing 8 family member A protein (LRRC8A) belongs the LRRC8 family of proteins within the LRR superfamily of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions (1,2). LRRC8A is a four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation (1). LRRC8A has also been shown to be an essential component of the volume-regulated anion channel VRAC (3).
- Molecular Weight
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Predicted: 89 kDa
Observed: 95 kDa - Gene ID
- 56262
- NCBI Accession
- NP_062540
- UniProt
- Q8IWT6
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