Prostate Specific Antigen antibody (total)
Quick Overview for Prostate Specific Antigen antibody (total) (ABIN264054)
Target
See all Prostate Specific Antigen (PSA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- total
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Specificity
- This antibody recognizes Prostate Specific Antigen. No cross reactivity with Human Albumin, AFP, CEA, PAP, CA-125, CA 19-9 or CA 15-3.Aff. Const.:6 x 109 L/m
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Characteristics
- Synonyms: Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
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Purification
- DEAE Column Chromatography
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Immunogen
- Human Total PSA
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Isotype
- IgG1
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Application Notes
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For enzyme conjugation. Pairs with MAb to free PSA Catalog #ABIN264052 in a sandwichimmunoassay for free PSA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 5.98 mg/mL (OD280nm)
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Buffer
- 0.015 M Potassium phosphate buffer, pH 7.4 containing 0.85 % Sodium Chloride, 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- Prostate Specific Antigen (PSA)
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Alternative Name
- Kallikrein-3 / PSA / KLK3
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Background
- PSA is a tumor-associated antigen with a molecular weight of 34 kDa. The antigen is found in normal prostatic epithelial lining cells of the ducts and acini, as well as in primary and metastatic prostate carcinoma cells. PSA reactivity may also be found in BPH (benign prostatic hypertrophy), though the pattern of staining is different than that found in carcinoma tissues. The staining pattern ranges from cytoplasmic and secretory in normal and benign prostate to cytoplasmic with membrane in neoplastic prostate.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase
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Gene ID
- 354
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UniProt
- P07288
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Pathways
- Complement System
Target
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