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CDKN2D antibody (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4))

Details for Product anti-CDKN2D Antibody No. ABIN264337, Supplier: Log in to see
Antigen
  • ink4d
  • p19
  • p19-ink4d
  • CDKN2D
  • ank2
  • INK4D
  • p19-INK4D
  • INK4d
  • p19INK4d
Alternatives
anti-Human CDKN2D antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Human
64
15
14
Host
Mouse
36
28
Clonality (Clone)
Monoclonal ()
Conjugate
This CDKN2D antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
38
19
18
12
12
11
8
6
4
3
1
1
Supplier
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Immunogen his-tagged recombinant full length p19 protein recognizing a 19kD protein.
Clone DCS-100
Isotype IgG1
Characteristics Synonyms: p19-INK4d, p19, INK4D, Cyclin-dependent kinase 4 inhibitor D
Purification Purified
Alternative Name CDKN2D / p19INK4d (CDKN2D Antibody Abstract)
Background The p19ink4d tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16 ink4a and p15ink4b. p19nk4d is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.Synonyms: Cyclin-dependent kinase 4 inhibitor D, INK4D, p19, p19-INK4d
Gene ID 1032
UniProt P55273
Pathways Cell Division Cycle
Application Notes Western Blot. Immunoprecipitation: co-precipitates cdk4/cdk6. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS with 0.08 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Expiry Date 12 months
Background publications Hirai, Roussel, Kato et al.: "Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2672-81, 1995 (PubMed).