Did you know that you can buy products from over 140 different suppliers from us?

Visual System Homeobox 2 (VSX2) (N-Term), (AA 1-131) antibody

Details for Product No. ABIN265011
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms VSX2, CHX10, c-ret, cret, etID315074.13, ret1, wu:fd13h01, RET1, HOX10, MCOP2, MCOPCB3, or, Chx10, Hox10, Hox-10, Vsx-2, alx, chx10
Epitope
N-Term, AA 1-131
(16), (8), (4), (3), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus)
(31), (23), (19), (14), (13), (12), (10)
Host
Sheep
(42), (10), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(37), (20), (10), (9), (6), (6), (4), (3), (2), (1)
Pubmed 3 references available
Quantity 0.25 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN265011
324.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Antibody raised against a recombinant protein corresponding to amino acids 1 to 131 derived from the N terminal of the human Chx10 protein conjugated to GST.
Isotype IgG
Specificity This antibody reacts to chx 10 (N-Term).
Purification Purified
Alternative Name VSX2 / CHX10
Background Chx10 is a 46kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.
Alternate names: Ceh-10 homeodomain-containing homolog, HOX10, Homeobox protein CHX10, Visual system homeobox 2
Gene ID 12677
NCBI Accession NP_031727
UniProt Q61412
Application Notes Western Blot: 0.5-1.0 mg/ml. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Immunohistochemistry on Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.08% Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C. Can be shipped at ambient temperature.
Expiry Date 12 months
Supplier Images
anti-Visual System Homeobox 2 (VSX2) (N-Term), (AA 1-131) antibody anti-Visual System Homeobox 2 (VSX2) (N-Term), (AA 1-131) antibody
Background publications Liu, Chen, Ploder et al.: "Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer." in: Neuron, Vol. 13, Issue 2, pp. 377-93, 1994 (PubMed).

Chen, Cepko: "Expression of Chx10 and Chx10-1 in the developing chicken retina." in: Mechanisms of development, Vol. 90, Issue 2, pp. 293-7, 2000 (PubMed).

Ferda Percin, Ploder, Yu et al.: "Human microphthalmia associated with mutations in the retinal homeobox gene CHX10." in: Nature genetics, Vol. 25, Issue 4, pp. 397-401, 2000 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN265011
324.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
Did you look for something else?
back to top