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GABBR1 antibody

GABBR1 Reactivity: Human, Rat, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265426
  • Target See all GABBR1 Antibodies
    GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
    Reactivity
    • 55
    • 50
    • 38
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 43
    • 20
    • 3
    • 2
    Rabbit
    Clonality
    • 48
    • 20
    Polyclonal
    Conjugate
    • 43
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABBR1 antibody is un-conjugated
    Application
    • 59
    • 21
    • 18
    • 17
    • 15
    • 14
    • 14
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of GABA-B Receptor protein. (region surrounding Ile902)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product GABBR1 Primary Antibody
  • Application Notes
    ELISA: 1/5000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
    Alternative Name
    GABBR1 (GABBR1 Products)
    Synonyms
    GABABR1 antibody, GABBR1-3 antibody, GB1 antibody, GPRC3A antibody, dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, gabbr1 antibody, GABBR1 antibody, GABA(B)R1 antibody, GABAB1 antibody, GABAbR1 antibody, bM573K1.1 antibody, gamma-aminobutyric acid type B receptor subunit 1 antibody, gamma-aminobutyric acid (GABA) B receptor, 1a antibody, gamma-aminobutyric acid (GABA) B receptor, 1 antibody, GABBR1 antibody, gabbr1a antibody, gabbr1 antibody, Gabbr1 antibody
    Background
    GAD-65 and GAD-67, glutamate decarboxylases of 65 kDa and 67 kD,arespectively, function to catalyze the production of GABA (gamma-aminobutyricacid). In the central nervous system GABA (gamma-aminobutyric acid)functions as the main inhibitory transmitter by increasing a Cl-conductancethat inhibits neuronal firing. GABA has been shown to activate bothionotropic (GABAA) and metabotropic (GABAB) receptors as well as a thirdclass of receptors called GABAC. The inhibitory neurotransmitter, GABA, acts through two ligand gated channels, GABAa and GABAc receptors and GABAb, the latter of which acts through a G protein mechanism. GABAbR1 is one of two G protein coupled receptors for GABAb that acts as a heteromeric assembly with GABAbR2.Synonyms: GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, Gb1
    Molecular Weight
    approx. 110 kDa
    Gene ID
    2550
    NCBI Accession
    NP_001461
    UniProt
    Q9UBS5
    Pathways
    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
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