CCR1 antibody (Alexa Fluor 488)

Catalog No. ABIN2657064

Product Details anti-CCR1 Antibody (Alexa Fluor 488)

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR1 antibody is conjugated to Alexa Fluor 488

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Mouse (Murine)

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.

Clone: 5F10B29

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Alternative Name: CD191 (CCR1 Products)

Synonyms: CD191 antibody, CKR-1 antibody, CKR1 antibody, CMKBR1 antibody, HM145 antibody, MIP1aR antibody, SCYAR1 antibody, Cmkbr1 antibody, Mip-1a-R antibody, C-C motif chemokine receptor 1 antibody, chemokine (C-C motif) receptor 1 antibody, CCR1 antibody, Ccr1 antibody

Background: CD191, also known as CCR1, is a 41 kD, G-protein coupled receptor expressed predominantly by monocytes. CCR1 is also expressed by a subset of T cells and eosinophils. CCR1 positive cells can migrate in response to a CCL3 and CCL5 gradient. CCR1 knock-out studies suggest that this molecule plays an important role in inflammation and susceptibility to viruses and parasites.