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CXCR2 antibody (Alexa Fluor 488)
CXCR2
Reactivity: Human
IHC, FACS
Host: Mouse
Monoclonal
5E8-CXCR2
Alexa Fluor 488
Product Details anti-CXCR2 Antibody (Alexa Fluor 488)
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Target
See all CXCR2 Antibodies
CXCR2
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
Reactivity
All reactivities for CXCR2 antibodies
Human
Host
All hosts for CXCR2 antibodies
Mouse
Clonality
All clonalities for CXCR2 antibodies
Monoclonal
Conjugate
All conjugates for CXCR2 antibodies
This CXCR2 antibody is conjugated to Alexa Fluor 488
Application
All applications for CXCR2 antibodies
Immunohistochemistry (IHC), Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone
5E8-CXCR2
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CXCR2
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Target
CXCR2
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
Alternative Name
CD182 (CXCR2 Products )
Synonyms
CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody
Background
CXCR2 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor B (IL-8RB), CD182, and CD128b. It is a CXC chemokine receptor belongs to G protein-coupled receptor (GPCR) family. CXCR2 is expressed as homodimer or heterodimer with CXCR1 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. CXCR2 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α,β,γ (CXCL1, CXCL2, CXCL3).
Pathways
cAMP Metabolic Process
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