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CD161 antibody (Alexa Fluor 647)
KLRB1
Reactivity: Human
FACS
Host: Mouse
Monoclonal
HP-3G10
Alexa Fluor 647
Product Details anti-CD161 Antibody (Alexa Fluor 647)
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Target
See all CD161 (KLRB1) Antibodies
CD161 (KLRB1)
(Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
Reactivity
All reactivities for CD161 antibodies
Human
Host
All hosts for CD161 antibodies
Mouse
Clonality
All clonalities for CD161 antibodies
Monoclonal
Conjugate
All conjugates for CD161 antibodies
This CD161 antibody is conjugated to Alexa Fluor 647
Application
All applications for CD161 antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Baboon, Chimpanzee, Rhesus Monkey
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
HP-3G10
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CD161
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Target
CD161 (KLRB1)
(Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
Alternative Name
CD161 (KLRB1 Products )
Synonyms
NKR-P1 antibody, KLRB1 antibody, 4930431A04Rik antibody, Gm4696 antibody, Klrb1g antibody, Klrb6 antibody, Ly-55 antibody, Ly55 antibody, NKR-P1G antibody, Nkrp-1e antibody, Nkrp1g antibody, CD161 antibody, CLEC5B antibody, NKR antibody, NKR-P1A antibody, NKRP1A antibody, hNKR-P1A antibody, Klrb1d antibody, Klrb1f antibody, Nkr-p1e antibody, killer cell lectin like receptor B1 antibody, killer cell lectin-like receptor subfamily B member 1 antibody, killer cell lectin-like receptor subfamily B, member 1 antibody, KLRB1 antibody, Klrb1 antibody
Background
CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
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