NKp44/NCR2 antibody (Alexa Fluor 647)

Catalog No. ABIN2657757

Product Details anti-NKp44/NCR2 Antibody (Alexa Fluor 647)

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NKp44/NCR2 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone: P44-8

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for NKp44/NCR2

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Alternative Name: CD336 (NCR2 Products)

Synonyms: CD336 antibody, LY95 antibody, NK-p44 antibody, NKP44 antibody, dJ149M18.1 antibody, uncharacterized LOC609023 antibody, natural cytotoxicity triggering receptor 2 antibody, LOC609023 antibody, NCR2 antibody

Background: CD336 is also known as activating NK receptor NKp44 (NKp44), natural cytotoxicity triggering receptor 2, and lymphocyte antigen 95 homolog. It is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp44 has an apparent molecular weight of 44 kD and three isoforms are produced by alternative splicing. NKp44 is expressed on IL-2 activated NK cells and a subset of γ/δ T cells. NKp44 enhances NK cell mediated cytolysis of virus infected cells and tumor cells. NKp44 has been shown to associate with the intracellular adaptor DAP12.