Integrin alpha 1 antibody (APC)

Catalog No. ABIN2658243

Product Details anti-Integrin alpha 1 Antibody (APC)

Target: Integrin alpha 1 (ITGA1)

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This Integrin alpha 1 antibody is conjugated to APC

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: HMalpha1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: CD49a (ITGA1 Products)

Synonyms: CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody

Background: CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex