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CXCR3 antibody (PE-Cy7)
CXCR3
Reactivity: Mouse
WB, IHC, IF, ICC, IP, ICFC, CT
Host: Hamster
Monoclonal
CXCR3-173
PE-Cy7
Product Details anti-CXCR3 Antibody (PE-Cy7)
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Target
See all CXCR3 Antibodies
CXCR3
(Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
Reactivity
All reactivities for CXCR3 antibodies
Mouse
Host
All hosts for CXCR3 antibodies
Hamster
Clonality
All clonalities for CXCR3 antibodies
Monoclonal
Conjugate
All conjugates for CXCR3 antibodies
This CXCR3 antibody is conjugated to PE-Cy7
Application
All applications for CXCR3 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC), Cell Tracking (CT)
Purification
The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
Clone
CXCR3-173
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.2 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CXCR3
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Target
CXCR3
(Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
Alternative Name
CD183 (CXCR3 Products )
Synonyms
CD182 antibody, CD183 antibody, CKR-L2 antibody, CMKAR3 antibody, GPR9 antibody, IP10-R antibody, Mig-R antibody, MigR antibody, Cd183 antibody, Cmkar3 antibody, CXCR3 antibody, cxcr3 antibody, Gpr9 antibody, CXC-R3 antibody, CXCR-3 antibody, zgc:92301 antibody, sb:eu378 antibody, C-X-C motif chemokine receptor 3 antibody, chemokine (C-X-C motif) receptor 3 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 antibody, CXCR3 antibody, Cxcr3 antibody, cxcr3 antibody, cxcr3.2 antibody, cxcr3.1 antibody
Background
CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes, or granulocytes.
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