CD39 antibody (PE-Cy7)

Catalog No. ABIN2659504

Product Details anti-CD39 Antibody (PE-Cy7)

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD39 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Cross-Reactivity: Rhesus Monkey

Purification: The antibody was purified by affinity chromatography, and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

Clone: A1

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD39

Target: CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))

Alternative Name: CD39 (ENTPD1 Products)

Synonyms: ATPDase antibody, CD39 antibody, NTPDase-1 antibody, MGC80631 antibody, zgc:100819 antibody, entpd1 antibody, MGC79567 antibody, 2610206B08Rik antibody, AA408691 antibody, Cd39 antibody, ectonucleoside triphosphate diphosphohydrolase 1 antibody, ectonucleoside triphosphate diphosphohydrolase 1 L homeolog antibody, ENTPD1 antibody, Entpd1 antibody, entpd1.L antibody, entpd1 antibody

Background: Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.