TCR Vbeta1 antibody (PerCP-Cy5.5)

Catalog No. ABIN2660244

Product Details

Target: TCR Vbeta1

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.

Clone: BL37-2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: TCR Vbeta1

Alternative Name: TCR V Beta1

Background: TCR Vβ1 is a variant of the TCR Vβ chain that is expressed by a subset of αβ+ T cells. Aberrant expression of TCR Vβ chains has been associated with infection and cancer. TCR Vβ1 is reported to be preferably used by autoreactive T cells in a model of autoimmune thyroiditis and diabetes. Skewing of TCR Vβ repertoire to Vβ1 and Vβ9 has also been reported in patients with multiple sclerosis, reactive arthritis, and Kawasaki disease.