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ICOSLG antibody (Biotin)

ICOSLG Reactivity: Mouse FACS Host: Rat Monoclonal HK5-3 Biotin
Catalog No. ABIN2661025
  • Target See all ICOSLG Antibodies
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    Reactivity
    • 68
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 44
    • 25
    • 3
    • 1
    Rat
    Clonality
    • 40
    • 32
    • 1
    Monoclonal
    Conjugate
    • 47
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICOSLG antibody is conjugated to Biotin
    Application
    • 43
    • 36
    • 23
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    HK5-3
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product ICOSLG Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
    Alternative Name
    CD275 (ICOSLG Products)
    Synonyms
    ICOSLG antibody, AU044799 antibody, B7-H2 antibody, B7RP-1 antibody, B7h antibody, BG071784 antibody, GI50 antibody, GL50 antibody, GL50-B antibody, ICOS-L antibody, Icoslg antibody, LICOS antibody, Ly115l antibody, mKIAA0653 antibody, B7H2 antibody, B7RP1 antibody, CD275 antibody, ICOSL antibody, Icosl antibody, RGD1562791 antibody, inducible T-cell costimulator ligand antibody, icos ligand antibody, inducible T-cell co-stimulator ligand antibody, ICOSLG antibody, Icosl antibody, Icoslg antibody
    Background
    CD275 is a 40 kD protein, also known as ICOS ligand, B7-RP1, B7-H2, and B7h. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells, and macrophages. The expression of this antigen is increased by TNF-α stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.
    Pathways
    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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