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ICOSLG antibody (Biotin)
ICOSLG
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
HK5-3
Biotin
Product Details anti-ICOSLG Antibody (Biotin)
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Target
See all ICOSLG Antibodies
ICOSLG
(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
Reactivity
All reactivities for ICOSLG antibodies
Mouse
Host
All hosts for ICOSLG antibodies
Rat
Clonality
All clonalities for ICOSLG antibodies
Monoclonal
Conjugate
All conjugates for ICOSLG antibodies
This ICOSLG antibody is conjugated to Biotin
Application
All applications for ICOSLG antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone
HK5-3
Isotype
IgG2a kappa
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Discover our top product ICOSLG Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for ICOSLG
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Target
ICOSLG
(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))
Alternative Name
CD275 (ICOSLG Products )
Synonyms
ICOSLG antibody, AU044799 antibody, B7-H2 antibody, B7RP-1 antibody, B7h antibody, BG071784 antibody, GI50 antibody, GL50 antibody, GL50-B antibody, ICOS-L antibody, Icoslg antibody, LICOS antibody, Ly115l antibody, mKIAA0653 antibody, B7H2 antibody, B7RP1 antibody, CD275 antibody, ICOSL antibody, Icosl antibody, RGD1562791 antibody, inducible T-cell costimulator ligand antibody, icos ligand antibody, inducible T-cell co-stimulator ligand antibody, ICOSLG antibody, Icosl antibody, Icoslg antibody
Background
CD275 is a 40 kD protein, also known as ICOS ligand, B7-RP1, B7-H2, and B7h. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells, and macrophages. The expression of this antigen is increased by TNF-α stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution.
Pathways
Production of Molecular Mediator of Immune Response , Activated T Cell Proliferation
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