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ICOSLG Products

(Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Categories

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion\; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function (By similarity).

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Featured ICOSLG Categories

ICOSLG Antibodies

High quality antibodies with extensive validation data.

ICOSLG ELISA Kits

Reliable ELISA kits for a wide range of species.

ICOSLG Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ICOSLG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (10)
Cat. No. ABIN7439975
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, IF, Coat, StM
Validations
  • (6)
Cat. No. ABIN6939407
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN7193325
Quantity 0.1 mg
Datasheet Datasheet

Recommended ICOSLG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967585
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967586
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956726
Quantity 96 tests
Datasheet Datasheet

Recommended ICOSLG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7273967
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273958
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273968
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ICOSLG products

Raineri, Dianzani, Cappellano, Maione, Baldanzi, Iacobucci, Clemente, Baldone, Boggio, Gigliotti, Boldorini, Rojo, Monti, Birolo, Dianzani, Chiocchetti: "Osteopontin binds ICOSL promoting tumor metastasis." in: Communications biology, Vol. 3, Issue 1, pp. 615, (2020) (PubMed).

Ma, Sun, Zhai, Yu, Wang, Li, Ding: "Effect of follicular helper T cells on the pathogenesis of asthma." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 967-972, (2017) (PubMed).

Schulte, Gielen, Kers-Rebel, Schreibelt, van Kuppeveld, Adema: "Enterovirus-infected β-cells induce distinct response patterns in BDCA1+ and BDCA3+ human dendritic cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121670, (2015) (PubMed).

Cairo, Surendran, Harris, Mazan-Mamczarz, Sakoda, Diaz-Mendez, Tamada, Gartenhaus, Mann, Pauza: "V?2V?2 T cell Costimulation Increases NK cell Killing of Monocyte-derived Dendritic Cells." in: Immunology, (2014) (PubMed).

Dianzani, Minelli, Gigliotti, Occhipinti, Giovarelli, Conti, Boggio, Shivakumar, Baldanzi, Malacarne, Orilieri, Cappellano, Fantozzi, Sblattero, Yagi, Rojo, Chiocchetti, Dianzani: "B7h triggering inhibits the migration of tumor cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4921-31, (2014) (PubMed).

Weissmüller, Semmler, Kalinke, Christians, Müller-Berghaus, Waibler: "ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation." in: Blood, Vol. 119, Issue 26, pp. 6268-77, (2012) (PubMed).

Fos, Salles, Lang, Carrette, Audebert, Pastor, Ghiotto, Olive, Bismuth, Nunès: "ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1969-77, (2008) (PubMed).

Jang, Park, Choi, Kim, Hwang, Baek, Suh, Mun, Suh: "12-O-tetradecanoyl phorbol 13-acetate induces the expression of B7-DC, -H1, -H2, and -H3 in K562 cells." in: International journal of oncology, Vol. 31, Issue 6, pp. 1439-47, (2007) (PubMed).

Youngnak-Piboonratanakit, Tsushima, Otsuki, Igarashi, Omura, Azuma: "Expression and regulation of human CD275 on endothelial cells in healthy and inflamed mucosal tissues." in: Scandinavian journal of immunology, Vol. 63, Issue 3, pp. 191-8, (2006) (PubMed).

Petroff, Kharatyan, Torry, Holets: "The immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placenta." in: The American journal of pathology, Vol. 167, Issue 2, pp. 465-73, (2005) (PubMed).

Synonyms and alternative names related to ICOSLG

inducible T-cell costimulator ligand (ICOSLG), icos ligand (Icosl), inducible T-cell co-stimulator ligand (Icoslg), AU044799, B7-H2, B7h, B7H2, B7RP-1, B7RP1, BG071784, CD275, GI50, GL50, GL50-B, ICOS-L, ICOSL, Icosl, ICOSLG, Icoslg, LICOS, Ly115l, mKIAA0653, RGD1562791

Protein level used designations for ICOSLG

  • CD80-like protein
  • ICOS ligand
  • inducible T-cell co-stimulator ligand
  • B7 homolog 2
  • B7-like protein Gl50
  • B7-related protein 1
  • B7 homologue 2
  • transmembrane protein B7-H2 ICOS ligand
  • icos ligand
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