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Integrin beta 4 antibody (FITC)
ITGB4
Reactivity: Human
WB
Host: Mouse
Monoclonal
58XB4
FITC
Product Details anti-Integrin beta 4 Antibody (FITC)
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Target
See all Integrin beta 4 (ITGB4) Antibodies
Integrin beta 4 (ITGB4)
Reactivity
All reactivities for Integrin beta 4 antibodies
Human
Host
All hosts for Integrin beta 4 antibodies
Mouse
Clonality
All clonalities for Integrin beta 4 antibodies
Monoclonal
Conjugate
All conjugates for Integrin beta 4 antibodies
This Integrin beta 4 antibody is conjugated to FITC
Application
All applications for Integrin beta 4 antibodies
Western Blotting (WB)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
58XB4
Isotype
IgG2a kappa
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for Integrin beta 4
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Target
Integrin beta 4 (ITGB4)
Alternative Name
CD104 (ITGB4 Products )
Synonyms
AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
Background
CD104 is a 205 kD type I transmembrane glycoprotein, known as integrin β4 chain or β4 integrin, that associates with integrin α6 (CD49f) forms α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD49f/CD104 is an adhesion receptor for laminins (especially laminin 5) and keratin filaments and is involved in the regulation of hemidesmosome formation and of cell proliferation and activation.
Pathways
Integrin Complex
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