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CXCR3 antibody (FITC)
CXCR3
Reactivity: Human
FACS
Host: Mouse
Monoclonal
G025H7
FITC
Product Details anti-CXCR3 Antibody (FITC)
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Target
See all CXCR3 Antibodies
CXCR3
(Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
Reactivity
All reactivities for CXCR3 antibodies
Human
Host
All hosts for CXCR3 antibodies
Mouse
Clonality
All clonalities for CXCR3 antibodies
Monoclonal
Conjugate
All conjugates for CXCR3 antibodies
This CXCR3 antibody is conjugated to FITC
Application
All applications for CXCR3 antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Cynomolgus, Rhesus Monkey
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
G025H7
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CXCR3
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Target
CXCR3
(Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
Alternative Name
CD183 (CXCR3 Products )
Synonyms
CD182 antibody, CD183 antibody, CKR-L2 antibody, CMKAR3 antibody, GPR9 antibody, IP10-R antibody, Mig-R antibody, MigR antibody, Cd183 antibody, Cmkar3 antibody, CXCR3 antibody, cxcr3 antibody, Gpr9 antibody, CXC-R3 antibody, CXCR-3 antibody, zgc:92301 antibody, sb:eu378 antibody, C-X-C motif chemokine receptor 3 antibody, chemokine (C-X-C motif) receptor 3 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 antibody, CXCR3 antibody, Cxcr3 antibody, cxcr3 antibody, cxcr3.2 antibody, cxcr3.1 antibody
Background
Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
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