Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibody (FITC)

Details for Product No. ABIN2661696, Supplier: Log in to see
Antigen
  • ENTPD1
  • MGC80631
  • zgc:100819
  • entpd1
  • MGC79567
  • ATPDase
  • CD39
  • NTPDase-1
  • 2610206B08Rik
  • AA408691
  • Cd39
  • ectonucleoside triphosphate diphosphohydrolase 8
  • ectonucleoside triphosphate diphosphohydrolase 1
  • ENTPD8
  • entpd1
  • ENTPD1
  • Entpd1
Reactivity
Human
151
90
36
5
4
4
4
2
1
1
1
1
Host
Mouse
119
43
42
5
3
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
23
13
9
9
7
6
6
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
119
107
54
26
24
22
14
7
6
2
2
2
2
2
1
1
1
1
Options
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Available images

Clone A1
Isotype IgG1 kappa
Cross-Reactivity Rhesus Monkey
Purification The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Alternative Name CD39 (ENTPD1 Antibody Abstract)
Background Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.
Research Area Immunology, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.
Supplier Images
Flow Cytometry (FACS) image for anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibody (FITC) (ABIN2661696) anti-Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) antibody (FITC)
Background publications Lyck, Dalmau, Chemnitz, Finsen, Schrøder: "Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 56, Issue 3, pp. 201-21, 2008 (PubMed).

Borsellino, Kleinewietfeld, Di Mitri, Sternjak, Diamantini, Giometto, Höpner, Centonze, Bernardi, DellAcqua, Rossini, Battistini, Rötzschke, Falk: "Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression." in: Blood, Vol. 110, Issue 4, pp. 1225-32, 2007 (PubMed).

Sestak, Scheiners, Wu, Hollemweguer: "Identification of anti-human CD antibodies reactive with rhesus macaque peripheral blood cells." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 21-6, 2007 (PubMed).

Stöckl, Majdic, Fischer, Maurer, Knapp: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, 2001 (PubMed).