ITGA6 antibody (FITC)

Catalog No. ABIN2661762

Product Details anti-ITGA6 Antibody (FITC)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Cross-Reactivity: Baboon, Cynomolgus, Rhesus Monkey, Horse (Equine), Cow (Bovine), Sheep (Ovine), Pig (Porcine), Dog (Canine), Cat (Feline), Rabbit, Capuchin Monkey, Chicken, Chimpanzee

Purification: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Clone: GoH3

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: CD49f (ITGA6 Products)

Synonyms: CD49f antibody, ITGA6B antibody, VLA-6 antibody, 5033401O05Rik antibody, AI115430 antibody, Cd49f antibody, ITGA6 antibody, inta6 antibody, im:6897425 antibody, itga6 antibody, si:dkey-32o22.1 antibody, wu:fb80g02 antibody, LOC100221694 antibody, si:dkey-18j14.1 antibody, wu:fl20e08 antibody, zgc:113088 antibody, integrin subunit alpha 6 antibody, integrin alpha 6 antibody, integrin subunit alpha 6 L homeolog antibody, integrin, alpha 6a antibody, integrin, alpha 6b antibody, ITGA6 antibody, Itga6 antibody, itga6.L antibody, itga6a antibody, itga6b antibody

Background: CD49f is a 120 kD integrin family member also known as VLA-6 α chain and α6 integrin subunit. CD49f associates with either integrin β1 (CD29) or integrin β4 (CD104) to form receptors (VLA-6 or α6β4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, and epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation.

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex