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CD94 antibody (FITC)
KLRD1
Reactivity: Mouse
WB, FACS, IHC, IP
Host: Rat
Monoclonal
18d3
FITC
Product Details anti-CD94 Antibody (FITC)
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Target
See all CD94 (KLRD1) Antibodies
CD94 (KLRD1)
(Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
Reactivity
All reactivities for CD94 antibodies
Mouse
Host
All hosts for CD94 antibodies
Rat
Clonality
All clonalities for CD94 antibodies
Monoclonal
Conjugate
All conjugates for CD94 antibodies
This CD94 antibody is conjugated to FITC
Application
All applications for CD94 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
18d3
Isotype
IgG2a kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD94
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Target
CD94 (KLRD1)
(Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
Alternative Name
CD94 (KLRD1 Products )
Synonyms
CD94 antibody, CD94-B antibody, Cd94 antibody, killer cell lectin like receptor D1 antibody, killer cell lectin-like receptor subfamily D, member 1 antibody, killer cell lectin-like receptor, subfamily D, member 1 antibody, KLRD1 antibody, Klrd1 antibody
Background
CD94 is a 43/39 kD C-type lectin, also known as Kp43. It is present on all NK cells, NK-T cells, and a subset of CD8-positive T lymphocytes in most mouse strains. CD94 is a type-II transmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail. CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediate signal transduction. When associated with NKG2A, the complex triggers inhibition, when associated with NKG2C, the complex triggers stimulation. The receptor complex of CD94 and NKG2 receptors bind to the ligand, Qa-1, and are thought to play a role in maintaining self-tolerance in developing NK cells.
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