CD1d antibody (PE)

Catalog No. ABIN2662517

Product Details anti-CD1d Antibody (PE)

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1d antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: 51-1

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD1d

Target: CD1d (CD1D) (CD1d Molecule (CD1D))

Alternative Name: CD1d (CD1D Products)

Synonyms: CD1A antibody, R3 antibody, CD1D antibody, CD1D1 antibody, CD1d molecule antibody, CD1D antigen, d polypeptide antibody, CD1D antibody

Background: CD1d is a MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily. On the cell surface, CD1d forms a heterodimer with β2-microglobulin. CD1d is expressed by antigen-presenting cells such as B cells, monocytes/macrophages, dendritic cells, and some non-lymphoid cells. Cortical thymocytes express CD1d but the expression is lost in mature T cells. CD1d presents lipid antigens to iNKT cells analogous to MHC molecule presentation of peptides to T cells.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process