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INPP5D antibody (PE)
INPP5D
Reactivity: Human, Mouse
FACS
Host: Mouse
Monoclonal
P1C1-A5
PE
Product Details anti-INPP5D Antibody (PE)
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Target
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INPP5D
(Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
Reactivity
All reactivities for INPP5D antibodies
Human, Mouse
Host
All hosts for INPP5D antibodies
Mouse
Clonality
All clonalities for INPP5D antibodies
Monoclonal
Conjugate
All conjugates for INPP5D antibodies
This INPP5D antibody is conjugated to PE
Application
All applications for INPP5D antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone
P1C1-A5
Isotype
IgG1 kappa
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Discover our top product INPP5D Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for INPP5D
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Target
INPP5D
(Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
Alternative Name
SHIP-1 (INPP5D Products )
Synonyms
INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody
Background
SH2-containing inositol phosphatase 1 (SHIP1) is a hematopoietic phosphatase that hydrolyzes key signaling lipid PI(3,4,5)P(3) to PI(3,4)P(2). SHIP-1 is located in the cytoplasm and is recruited to the cell surface upon receptor ligation. It plays critical roles in hematopoietic cell proliferation, activation, differentiation, and survival by regulating PI3K and Akt pathways. Aberrant regulation of PI3K signaling can induce autoimmune diseases and cancer formation.
Pathways
TCR Signaling , BCR Signaling , Warburg Effect
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