The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
FCAMR antibody, CD351 antibody, FCA/MR antibody, Fc fragment of IgA and IgM receptor antibody, Fc receptor, IgA, IgM, high affinity antibody, FCAMR antibody, Fcamr antibody
Target Type
Antibody
Background
Fcα/μ receptor (Fcα/μR), CD351, is a type I transmembrane protein with an Ig-like domain in extracellular portion. It is a novel Fc receptor for IgM and IgA. Fcα/μ receptor mRNA has been found in thymus, spleen, liver, kidney, intestines, testes, placenta, and T cell leukemia cell lines. Fcα/μ receptor protein expression is detected on B cells, macrophages, and activated T cells. Fcα/μ receptor mediates primary B lymphocyte endocytosis of IgM-coated Staphylococcus aureus. It is involved in the primary stages of the immune response to microbes.