DLL1 antibody (PE)

Catalog No. ABIN2663681

Product Details anti-DLL1 Antibody (PE)

Target: DLL1 (delta-Like 1 (DLL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL1 antibody is conjugated to PE

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: MHD1-314

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Alternative Name: delta-Like Protein 1 (DLL1 Products)

Synonyms: X-delta-1 antibody, XDelta1 antibody, Xdelta-1 antibody, delta antibody, delta-1 antibody, delta1 antibody, x-delta antibody, DELTA1 antibody, DL1 antibody, Delta antibody, DLK antibody, DLK-1 antibody, Delta1 antibody, FA1 antibody, PREF1 antibody, Pref-1 antibody, ZOG antibody, pG2 antibody, DLL1 antibody, AW742678 antibody, DlkI antibody, Ly107 antibody, Peg9 antibody, SCP1 antibody, pref-1 antibody, delta-like 1 antibody, delta like canonical Notch ligand 1 antibody, delta like non-canonical Notch ligand 1 antibody, delta-like 1 L homeolog antibody, delta-like 1 (Drosophila) antibody, delta-like 1 homolog (Drosophila) antibody, dll1 antibody, DLL1 antibody, DLK1 antibody, Dll1 antibody, dll1.L antibody, Dlk1 antibody

Background: Delta-like protein 1 is a type I transmembrane protein. The mature form consist of an extracellular domain of 528 amino acids (aa) that contain a DSL domain and eight tandem EGF repeats, the transmembrane region is 23 aa long and has a 155 aa cytoplasmic domain. After the binding of Notch receptors, the extracellular and cytoplasmic domains are cleaved, and the later is translocated into the cell nucleus to regulate gene expression. Delta-like protein 1 is expressed in heart and pancreas and in a lower amount in brain and muscle. During fetal life, it is transiently expressed during gastrulation and early organogenesis and its expression remains through adult life in hematopoietic tissues and the cortico-medullary region of the thymus.

Pathways: Notch Signaling, Stem Cell Maintenance