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IL-10 antibody (PE)

IL10 Reactivity: Mouse ELISA, IP, FACS Host: Rat Monoclonal JES5-16E3 PE
Catalog No. ABIN2663765
  • Target See all IL-10 (IL10) Antibodies
    IL-10 (IL10) (Interleukin 10 (IL10))
    Reactivity
    • 137
    • 83
    • 49
    • 19
    • 17
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 125
    • 62
    • 50
    • 4
    • 3
    • 1
    Rat
    Clonality
    • 128
    • 111
    • 1
    Monoclonal
    Conjugate
    • 158
    • 30
    • 12
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This IL-10 antibody is conjugated to PE
    Application
    • 168
    • 115
    • 79
    • 53
    • 40
    • 27
    • 23
    • 19
    • 17
    • 15
    • 14
    • 14
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    JES5-16E3
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product IL10 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-10 (IL10) (Interleukin 10 (IL10))
    Alternative Name
    IL-10 (IL10 Products)
    Synonyms
    CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody
    Background
    IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80 % sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones, inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis, suppresses the delayed type hypersensitivity response, stimulates Th2 cell response (which results in elevated antibody production), and promotes mast cell proliferation in combination with IL-4.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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