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PRDM1 antibody
PRDM1
Reactivity: Human
FACS
Host: Mouse
Monoclonal
ROS195G
unconjugated
Product Details anti-PRDM1 Antibody
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Target
See all PRDM1 Antibodies
PRDM1
(PR Domain Containing 1, with ZNF Domain (PRDM1))
Reactivity
All reactivities for PRDM1 antibodies
Human
Host
All hosts for PRDM1 antibodies
Mouse
Clonality
All clonalities for PRDM1 antibodies
Monoclonal
Conjugate
All conjugates for PRDM1 antibodies
This PRDM1 antibody is un-conjugated
Application
All applications for PRDM1 antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Mouse (Murine)
Purification
The antibody was purified by affinity chromatography.
Clone
ROS195G
Isotype
IgG1
Top Product
Discover our top product PRDM1 Primary Antibody
Alternatives
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anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) antibody
PRDM1
Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse, Guinea Pig
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for PRDM1
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Target
PRDM1
(PR Domain Containing 1, with ZNF Domain (PRDM1))
Alternative Name
Blimp-1 (PRDM1 Products )
Synonyms
GB11750 antibody, CG5249 antibody, Dmel\\CG5249 antibody, blimp-1 antibody, dBlimp-1 antibody, dBlimp1 antibody, Blimp-1 antibody, Blimp1 antibody, nrd antibody, prdm1 antibody, ubo antibody, wu:fb99c12 antibody, zgc:91885 antibody, MGC52536 antibody, PRDM1 antibody, blimp1 antibody, xblimp1 antibody, prdi-bf1 antibody, BLIMP1 antibody, PRDI-BF1 antibody, ZNFPR1A1 antibody, PR/SET domain 1 antibody, probable serine/threonine-protein kinase DDB_G0282963 antibody, CG5249 gene product from transcript CG5249-RF antibody, blimp-1 antibody, PR domain containing 1a, with ZNF domain antibody, PR domain 1 S homeolog antibody, B lymphocyte induced maturation protein 1 antibody, PR domain 1 antibody, PR domain containing 1, with ZNF domain antibody, PRDM1 antibody, LOC408295 antibody, Blimp-1 antibody, CpipJ_CPIJ007425 antibody, prdm1a antibody, prdm1.S antibody, prdm1 antibody, Prdm1 antibody
Background
Blimp-1 is a 98 Kd protein containing five Kuppel-type zinc finger domains that confer sequence specific DNA binding. It has been postulated to be a master regulator of terminal B cell differentiation. In the BCL-1 lymphoma model of differentiation from mature B cells to plasma cells, ectopic expression of Blimp-1 is sufficient to cause terminal differentiation manifested by loss of surface immunoglobulin, IgM secretion, expression of syndecan-1 and cessation of cell division. Recently, it is reported that Blimp-1 is also involved in T cell differentiation and T cell homeostasis and suppression of IL-2 production.
Pathways
Regulation of Muscle Cell Differentiation
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