CD52 antibody

Catalog No. ABIN2664761

Product Details anti-CD52 Antibody

Target: CD52

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD52 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography.

Clone: HI186

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD52

Target: CD52

Alternative Name: CD52 (CD52 Products)

Synonyms: CD52 antibody, AI463198 antibody, B7 antibody, B7-Ag antibody, CAMPATH-1 antibody, CLS1 antibody, MB7 antibody, CDW52 antibody, CE5 antibody, CD52 molecule antibody, CD52 antigen antibody, CD52 antibody, Cd52 antibody

Background: CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression. The HI186 antibody is useful for flow cytometry and immunohistochemistry.