IL33RA antibody
IL33RA
Reactivity: Mouse
IHC, FACS, BR, CyTOF
Host: Rat
Monoclonal
DIH9
unconjugated
1 image
-
- Target
- IL33RA (Interleukin 33 Receptor alpha (IL33RA))
- Reactivity
- Mouse
- Host
- Rat
- Clonality
- Monoclonal
- Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Blocking Reagent (BR), Cytometry by Time of Flight (CyTOF)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- DIH9
- Isotype
- IgG2a kappa
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- IL33RA (Interleukin 33 Receptor alpha (IL33RA))
- Alternative Name
- IL-33R alpha
- Background
- IL-33Rα, also known as ST2 or IL-1RL1, is a member of the Toll/IL-1 receptor family. It binds IL-33 and is structurally similar to IL-1R1. Two forms of the protein exist - a soluble form known as ST2 and a membrane anchored form known as ST2L. The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts. Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation. The IL-33-ST2 axis has been reported to be important across a range of diseases including asthma, allergies, and cardiac disease.
-
You are here:
