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CCL2 antibody
CCL2
Reactivity: Human, Mouse, Rat
WB, IHC, IP, FACS, ICFC
Host: Hamster
Monoclonal
2H5
unconjugated
Product Details anti-CCL2 Antibody
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Target
See all CCL2 Antibodies
CCL2
(Chemokine (C-C Motif) Ligand 2 (CCL2))
Reactivity
All reactivities for CCL2 antibodies
Human, Mouse, Rat
Host
All hosts for CCL2 antibodies
Hamster
Clonality
All clonalities for CCL2 antibodies
Monoclonal
Conjugate
All conjugates for CCL2 antibodies
This CCL2 antibody is un-conjugated
Application
All applications for CCL2 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
Cross-Reactivity
Rhesus Monkey
Purification
The antibody was purified by affinity chromatography.
Clone
2H5
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CCL2
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Target
CCL2
(Chemokine (C-C Motif) Ligand 2 (CCL2))
Alternative Name
MCP-1 (CCL2 Products )
Synonyms
GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
Background
Monocyte chemotactic protein-1 (MCP-1) also known as monocyte chemotactic and activating factor (MCAF) was identified based on its ability to chemoattract monocytes. Subsequently, MCP-1 has also been found to regulate adhesion molecule expression and cytokine production in monocytes. MCP-1 is identical to the product of the JE gene, a PDGF inducible gene. MCP-1 is a member of the beta (C-C) chemokine subfamily, known as CCL2. The 2H5 antibody reacts with mouse, rat, and human MCP-1. The 2H5 antibody can neutralize the bioactivity of natural or recombinant MCP-1.
Pathways
Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , ER-Nucleus Signaling , Unfolded Protein Response , The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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