CD209b Antigen (CD209B) antibody
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- Target See all CD209b Antigen (CD209B) Antibodies
- CD209b Antigen (CD209B)
- Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purified.
- Clone
- 2C7B27
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD209B Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Upon receipt, store undiluted between 2°C and 8°C.
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- Target
- CD209b Antigen (CD209B)
- Alternative Name
- CD209B (CD209B Products)
- Synonyms
- 1810030I22Rik antibody, OtB7 antibody, SIGNR1 antibody, mSIGNR1 antibody, CD209b antigen antibody, Cd209b antibody
- Background
- CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
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