SREBF1 antibody (AA 301-407)

Catalog No. ABIN2668814

Product Details anti-SREBF1 Antibody

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Binding Specificity: AA 301-407

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SREBF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Electrophoretic Mobility-Shift Assay (EMSA)

Purification: Protein G Chromatography

Immunogen: This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.

Clone: IgG-2A4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-SREBF1 antibody (ABIN2668814)

Rueda-Rincon, Bloch, Derua, Vyas, Harms, Hankemeier, Khan, Dehairs, Bagadi, Binda, Waelkens, Marine, Swinnen: "p53 attenuates AKT signaling by modulating membrane phospholipid composition." in: Oncotarget, Vol. 6, Issue 25, pp. 21240-54, (2015) (PubMed).

Daniëls, Smans, Royaux, Chypre, Swinnen, Zaidi: "Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment." in: PLoS ONE, Vol. 9, Issue 9, pp. e106913, (2014) (PubMed).

Target Details for SREBF1

Target: SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))

Alternative Name: SREBP-1 (SREBF1 Products)

Synonyms: SREBP-1c antibody, SREBP1 antibody, bHLHd1 antibody, ADD-1 antibody, ADD1 antibody, D630008H06 antibody, SREBP-1 antibody, SREBP-1a antibody, SREBP1c antibody, Srebp1 antibody, SCREBP1 antibody, SREBP-1C antibody, SREBF1 antibody, srebp1 antibody, sterol regulatory element binding transcription factor 1 antibody, sterol regulatory element binding transcription factor 1 L homeolog antibody, sterol regulatory element binding protein-1 antibody, Sterol regulatory element Binding Protein antibody, SREBF1 antibody, Srebf1 antibody, srebf1.L antibody, SREBP-1 antibody, srebf1 antibody, sbp-1 antibody

Molecular Weight: 68 and 125 kDa

Gene ID: 6720

Pathways: AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha