TXNRD2 antibody

Catalog No. ABIN271967

The Rabbit Polyclonal anti-TXNRD2 antibody is suitable to detect TXNRD2 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for TXNRD2 antibody (ABIN271967)

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNRD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TXNRD2 Antibody

Specificity: This antibody detects endogenous levels of TRXR2 protein. (region surrounding Ser51)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TXNRD2

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Alternative Name: Thioredoxin Reductase 2 / TXNRD2

Background: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.Synonyms: KIAA1652, SelZ, Selenoprotein Z, TR-beta, TRXR2, Thioredoxin reductase 2 mitochondrial, Thioredoxin reductase TR3

Molecular Weight: approx. 60,62 kDa

Gene ID: 10587

NCBI Accession: NP_006431

UniProt: Q9NNW7

Pathways: Cell RedoxHomeostasis