CSTF2 antibody

Catalog No. ABIN272180

Product Details anti-CSTF2 Antibody

Target: CSTF2 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa (CSTF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSTF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of CstF-64 protein. (region surrounding Arg46)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CSTF2

Target: CSTF2 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa (CSTF2))

Alternative Name: CSTF2 (CSTF2 Products)

Synonyms: CSTF2 antibody, CstF-64 antibody, fb11e07 antibody, zgc:56346 antibody, zgc:77730 antibody, wu:fb11e07 antibody, 64kDa antibody, C630034J23Rik antibody, Cstf64 antibody, CSFT64 antibody, cstF-64 antibody, cstf-64 antibody, cleavage stimulation factor subunit 2 antibody, cleavage stimulation factor, 3' pre-RNA, subunit 2 antibody, cleavage stimulation factor, 3' pre-RNA subunit 2 antibody, CSTF2 antibody, cstf2 antibody, Cstf2 antibody, cstf2.L antibody

Background: The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific. In the developing nervous system AKT is a critical mediator of growth factor induced neuronal survival. Survival factors can suppress apoptosis in a transcription independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene (referenced from entrez gene).Synonyms: CF-1 64 kDa subunit, CSTF 64 kDa subunit, CSTF64, Cleavage stimulation factor 64 kDa subunit, CstF-64

Molecular Weight: approx. 60 kDa

Gene ID: 1478

NCBI Accession: NP_001316

UniProt: P33240