YBX2 antibody
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- Target See all YBX2 Antibodies
- YBX2 (Y Box Binding Protein 2 (YBX2))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This YBX2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of MSY2 protein. (region surrounding Gly311)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human and Mouse.
- Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product YBX2 Primary Antibody
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- Application Notes
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ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- YBX2 (Y Box Binding Protein 2 (YBX2))
- Alternative Name
- YBX2 (YBX2 Products)
- Synonyms
- CONTRIN antibody, CSDA3 antibody, DBPC antibody, MSY2 antibody, RGD1305068 antibody, YBX2 antibody, dbpc antibody, msy2 antibody, csda3 antibody, frgy2 antibody, contrin antibody, csda antibody, csda-A antibody, p54 antibody, Msy2 antibody, frgy2-A antibody, Y-box binding protein 2 antibody, Y box binding protein 2 antibody, Y-box binding protein 2 S homeolog antibody, Y box protein 2 antibody, Y-box binding protein 2 L homeolog antibody, YBX2 antibody, Ybx2 antibody, ybx2 antibody, ybx2.S antibody, ybx2.L antibody
- Background
- Contrin (MSY2 in mouse) and YB-2 (MSY3/4 in mouse) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation.Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins. The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues. MSY2 (Contrin) is a expressed in testis and ovary, where it may repress translation of parental mRNA. The gene encoding human Contrin maps to chromosome 17p11.2-13.1. MSY3/4 (YB-2) is also known as DNA binding protein A and is highly expressed in testis, heart and muscle. Contrin and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2
- Molecular Weight
- approx. 38 kDa
- Gene ID
- 51087
- NCBI Accession
- NP_057066
- UniProt
- Q9Y2T7
- Pathways
- Chromatin Binding
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