YBX2 antibody

Catalog No. ABIN272262

Product Details anti-YBX2 Antibody

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of MSY2 protein. (region surrounding Gly311)

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for YBX2

Target: YBX2 (Y Box Binding Protein 2 (YBX2))

Alternative Name: YBX2 (YBX2 Products)

Synonyms: CONTRIN antibody, CSDA3 antibody, DBPC antibody, MSY2 antibody, RGD1305068 antibody, YBX2 antibody, dbpc antibody, msy2 antibody, csda3 antibody, frgy2 antibody, contrin antibody, csda antibody, csda-A antibody, p54 antibody, Msy2 antibody, frgy2-A antibody, Y-box binding protein 2 antibody, Y box binding protein 2 antibody, Y-box binding protein 2 S homeolog antibody, Y box protein 2 antibody, Y-box binding protein 2 L homeolog antibody, YBX2 antibody, Ybx2 antibody, ybx2 antibody, ybx2.S antibody, ybx2.L antibody

Background: Contrin (MSY2 in mouse) and YB-2 (MSY3/4 in mouse) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation.Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins. The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues. MSY2 (Contrin) is a expressed in testis and ovary, where it may repress translation of parental mRNA. The gene encoding human Contrin maps to chromosome 17p11.2-13.1. MSY3/4 (YB-2) is also known as DNA binding protein A and is highly expressed in testis, heart and muscle. Contrin and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2

Molecular Weight: approx. 38 kDa

Gene ID: 51087

NCBI Accession: NP_057066

UniProt: Q9Y2T7

Pathways: Chromatin Binding