PACS1 antibody (Internal Region)

Catalog No. ABIN2743435

Product Details anti-PACS1 Antibody

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACS1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human PACS1

Purification: Protein A purified

Immunogen: A recombinant protein fragment from the internal portion of human PACS-1.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: WB (1 - 3 μg/mL)

Usage: PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor). PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Alternative Name: PACS1 (PACS1 Products)

Synonyms: MRD17 antibody, AI325977 antibody, Pacs-1 antibody, phosphofurin acidic cluster sorting protein 1 antibody, PACS1 antibody, Pacs1 antibody

Background: Name/Gene ID: PACS1

Synonyms: PACS1, KIAA1175, PACS-1

Gene ID: 55690