PACS1 Products
(phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
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This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008].
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Featured PACS1 Categories
PACS1 Antibodies
High quality antibodies with extensive validation data.
Recommended PACS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7163266
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Opossum
Application
WB
Validations
- (1)
Cat. No.
ABIN960302
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6145155
Quantity
100 μL
Datasheet
Datasheet
Recommended PACS1 Proteins
Synonyms and alternative names related to PACS1
phosphofurin acidic cluster sorting protein 1 (PACS1), phosphofurin acidic cluster sorting protein 1 (Pacs1), AI325977, MRD17, Pacs-1Protein level used designations for PACS1
- PACS-1
- cytosolic sorting protein PACS-1
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