CCDC50 antibody (Middle Region)
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- Target See all CCDC50 Antibodies
- CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCDC50 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KAKEREKSSL DKRKQDPEWK PKTAKAANSK SKESDEPHHS KNERPARPPP
- Predicted Reactivity
- Cow: 93%, Dog: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against CCDC50. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CCDC50
- Top Product
- Discover our top product CCDC50 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 482 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))
- Alternative Name
- CCDC50 (CCDC50 Products)
- Synonyms
- ymer antibody, C3orf6 antibody, DFNA44 antibody, YMER antibody, 2610529H08Rik antibody, 5730448P06Rik antibody, AW048328 antibody, AW546090 antibody, D16Bwg1543e antibody, C3orf6h antibody, c3orf6 antibody, coiled-coil domain containing 50 antibody, coiled-coil domain containing 50 L homeolog antibody, CCDC50 antibody, ccdc50.L antibody, ccdc50 antibody, Ccdc50 antibody
- Background
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CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.
Alias Symbols: C3orf6, DFNA44, YMER
Protein Interaction Partner: UBC, SH3RF2, RIPK1, TNFAIP3, EGFR, RPS3A,
Protein Size: 482 - Molecular Weight
- 56 kDa
- Gene ID
- 152137
- NCBI Accession
- NM_178335, NP_848018
- UniProt
- Q8IVM0
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