HTRA4 antibody (Middle Region)
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- Target See all HTRA4 Antibodies
- HTRA4 (HtrA Serine Peptidase 4 (HTRA4))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Cow, Guinea Pig, Dog, Horse, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HTRA4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LKMHYPDFPD VSSGVYVCKV VEGTAAQSSG LRDHDVIVNI NGKPITTTTD
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against HTRA4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HTRA4
- Top Product
- Discover our top product HTRA4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 476 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HTRA4 (HtrA Serine Peptidase 4 (HTRA4))
- Alternative Name
- HTRA4 (HTRA4 Products)
- Synonyms
- B430206E18Rik antibody, RGD1306242 antibody, HtrA serine peptidase 4 antibody, HTRA4 antibody, Htra4 antibody
- Background
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HTRA4 is a member of the HtrA family of proteases. The protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
Alias Symbols: FLJ90724
Protein Size: 476 - Molecular Weight
- 51 kDa
- Gene ID
- 203100
- NCBI Accession
- NM_153692, NP_710159
- UniProt
- P83105
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