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FBXL5 antibody (Middle Region)

FBXL5 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774689
  • Target See all FBXL5 Antibodies
    FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
    Binding Specificity
    • 16
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog, Pig
    Host
    • 43
    • 3
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXL5 antibody is un-conjugated
    Application
    • 42
    • 28
    • 22
    • 21
    • 5
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VHWARGDWYS GPATELDTEP DDEWVKNRKD ESRAFHEWDE DADIDESEES
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against FBXL5. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FBXL5
    Top Product
    Discover our top product FBXL5 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 691 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
    Alternative Name
    FBXL5 (FBXL5 Products)
    Synonyms
    fbxl5 antibody, MGC53238 antibody, FBXL5 antibody, FBL4 antibody, FBL5 antibody, FLR1 antibody, Fbl4 antibody, Fir4 antibody, wu:fb52d06 antibody, F-box and leucine rich repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 S homeolog antibody, F-box and leucine-rich repeat protein 5 L homeolog antibody, F-box and leucine-rich repeat protein 5 antibody, FBXL5 antibody, fbxl5.S antibody, fbxl5.L antibody, fbxl5 antibody, Fbxl5 antibody
    Background
    FBXL5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL5 belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.
    Alias Symbols: FBL4, FBL5, FLR1
    Protein Interaction Partner: NABP2, CUL1, SNAI1, SKP1, FBXL5, HERC2, UBC, IREB2, ACO1, RBX1, MUS81, MMS19, FAM96B, ORC4, EP300, SMURF1, BTG1, COPS5, PLK1, CSNK2B, DCTN1,
    Protein Size: 691
    Molecular Weight
    76 kDa
    Gene ID
    26234
    NCBI Accession
    NM_012161, NP_036293
    UniProt
    Q9UKA1
    Pathways
    Transition Metal Ion Homeostasis
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