HERC3 antibody (Middle Region)

Catalog No. ABIN2774751

Product Details anti-HERC3 Antibody

Target: HERC3 (Hect Domain and RLD 3 (HERC3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LHFPLALYKK LLNVKPGLED LKELSPTEGR SLQELLDYPG EDVEETFCLN

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against HERC3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HERC3

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HERC3

Target: HERC3 (Hect Domain and RLD 3 (HERC3))

Alternative Name: HERC3 (HERC3 Products)

Synonyms: 5730409F18Rik antibody, AI646603 antibody, mKIAA0032 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 3 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 3 L homeolog antibody, probable E3 ubiquitin-protein ligase HERC3 antibody, hect domain and RLD 3 antibody, HERC3 antibody, herc3.L antibody, herc3 antibody, LOC100539754 antibody, LOC100563151 antibody, Herc3 antibody

Background: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Protein Size: 494

Molecular Weight: 54 kDa

Gene ID: 8916

NCBI Accession: NM_001271602, NP_001258531

UniProt: Q15034