IGLL1 antibody (N-Term)
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- Target See all IGLL1 Antibodies
- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IGLL1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RSRWGRFLLQ RGSWTGPRCW PRGFQSKHNS VTHVFGSGTQ LTVLSQPKAT
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IGLL1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human IGLL1
- Top Product
- Discover our top product IGLL1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 213 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
- Alternative Name
- IGLL1 (IGLL1 Products)
- Synonyms
- 14.1 antibody, AGM2 antibody, CD179b antibody, IGL1 antibody, IGL5 antibody, IGLJ14.1 antibody, IGLL antibody, IGO antibody, IGVPB antibody, VPREB2 antibody, IGLV antibody, IGLL1 antibody, MGC151892 antibody, Igll1 antibody, BB139905 antibody, Igl-5 antibody, Igll antibody, Lambda5 antibody, immunoglobulin lambda like polypeptide 1 antibody, immunoglobulin lambda-like polypeptide 1 antibody, IGLL1 antibody, Igll1 antibody
- Background
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The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 14.1, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2, AGM2
Protein Interaction Partner: MYOC, IGLL1,
Protein Size: 213 - Molecular Weight
- 19 kDa
- Gene ID
- 3543
- NCBI Accession
- NM_020070, NP_064455
- UniProt
- P15814
- Pathways
- Regulation of Cell Size
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