RGS18 antibody (Middle Region)
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- Target See all RGS18 Antibodies
- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RGS18 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EDFKKSKGPQ QIHLKAKAIY EKFIQTDAPK EVNLDFHTKE VITNSITQPT
- Predicted Reactivity
- Guinea Pig: 79%, Horse: 86%, Human: 100%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against RGS18. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RGS18
- Top Product
- Discover our top product RGS18 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 235 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
- Alternative Name
- RGS18 (RGS18 Products)
- Synonyms
- RGS18 antibody, rgs18 antibody, RGS13 antibody, regulator of G-protein signaling 18 antibody, regulator of G protein signaling 18 antibody, RGS18 antibody, rgs18 antibody, LOC100224724 antibody, Rgs18 antibody
- Background
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RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS13
Protein Interaction Partner: APP, GNAQ, GNAI3, GNAI2, GNAI1,
Protein Size: 235 - Molecular Weight
- 27 kDa
- Gene ID
- 64407
- NCBI Accession
- NM_130782, NP_570138
- UniProt
- Q9NS28
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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