Tricellulin antibody (Middle Region)

Catalog No. ABIN2775617

Product Details anti-Tricellulin Antibody

Target: Tricellulin (MARVELD2)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tricellulin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PKTPFVLVVA GLAWITTIII LVLGMSMYYR TILLDSNWWP LTEFGINVAL

Predicted Reactivity: Cow: 100%, Dog: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MARVELD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARVELD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 457 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tricellulin

Target: Tricellulin (MARVELD2)

Alternative Name: MARVELD2 (MARVELD2 Products)

Synonyms: Mrvldc2 antibody, BC003296 antibody, MARVD2 antibody, Tric antibody, Trica antibody, Tricb antibody, Tricc antibody, DFNB49 antibody, MRVLDC2 antibody, MARVEL domain containing 2 antibody, MARVEL (membrane-associating) domain containing 2 antibody, Marveld2 antibody, MARVELD2 antibody

Background: Tight junctions (TJ) prevent leakage of solutes through the paracellular pathway of epithelial cells. MARVELD2, or tricellulin (TRIC), is an integral membrane protein concentrated at the vertically oriented TJ strands of tricellular contacts (Ikenouchi et
Alias Symbols: DFNB49, FLJ30532, MARVD2, MRVLDC2, Tric
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 457

Molecular Weight: 52 kDa

Gene ID: 153562

NCBI Accession: NM_144724, NP_653325

UniProt: C9J8H4

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization