MARCH2 antibody (C-Term)

Catalog No. ABIN2775655

Product Details anti-MARCH2 Antibody

Target: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Binding Specificity: C-Term

Reactivity: Human, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IALFTIYVLW TLVSFRYHCQ LYSEWRKTNQ KVRLKIREAD SPEGPQHSPL

Predicted Reactivity: Guinea Pig: 90%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against MARCH2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARCH2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MARCH2

Target: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Alternative Name: MARCH2 (MARCH2 Products)

Synonyms: MARCH-II antibody, RNF172 antibody, rgd1306395 antibody, marh2 antibody, RGD1306395 antibody, 9530046H09Rik antibody, membrane associated ring-CH-type finger 2 antibody, membrane associated ring-CH-type finger 2 S homeolog antibody, E3 ubiquitin-protein ligase MARCH2 antibody, membrane-associated ring finger (C3HC4) 2 antibody, MARCH2 antibody, march2.S antibody, march2 antibody, Tsp_09446 antibody, marh2 antibody, March2 antibody

Background: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.
Alias Symbols: MARCH-II, RNF172
Protein Interaction Partner: LDLRAD1, SYNE4, CCDC155, FATE1, UBE2H, UBE2D1, CDC34, GOPC, STX6, CFTR, ADRB2, ELAVL1, DLG1,
Protein Size: 246

Molecular Weight: 27 kDa

Gene ID: 51257

NCBI Accession: NM_016496, NP_057580

UniProt: Q9P0N8