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MARCH2 antibody (C-Term)
MARCH2
Reactivity: Human, Guinea Pig, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MARCH2 Antibody
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Target
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MARCH2
(Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
Binding Specificity
All epitopes for MARCH2 antibodies
C-Term
Reactivity
All reactivities for MARCH2 antibodies
Human, Guinea Pig, Rabbit
Host
All hosts for MARCH2 antibodies
Rabbit
Clonality
All clonalities for MARCH2 antibodies
Polyclonal
Conjugate
All conjugates for MARCH2 antibodies
This MARCH2 antibody is un-conjugated
Application
All applications for MARCH2 antibodies
Western Blotting (WB)
Sequence
IALFTIYVLW TLVSFRYHCQ LYSEWRKTNQ KVRLKIREAD SPEGPQHSPL
Predicted Reactivity
Guinea Pig: 90%, Human: 100%, Rabbit: 79%
Characteristics
This is a rabbit polyclonal antibody against MARCH2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARCH2
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Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MARCH2
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Target
MARCH2
(Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
Alternative Name
MARCH2 (MARCH2 Products )
Synonyms
MARCH-II antibody, RNF172 antibody, rgd1306395 antibody, marh2 antibody, RGD1306395 antibody, 9530046H09Rik antibody, membrane associated ring-CH-type finger 2 antibody, membrane associated ring-CH-type finger 2 S homeolog antibody, E3 ubiquitin-protein ligase MARCH2 antibody, membrane-associated ring finger (C3HC4) 2 antibody, MARCH2 antibody, march2.S antibody, march2 antibody, Tsp_09446 antibody, marh2 antibody, March2 antibody
Background
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking. Alias Symbols: MARCH-II, RNF172 Protein Interaction Partner: LDLRAD1, SYNE4, CCDC155, FATE1, UBE2H, UBE2D1, CDC34, GOPC, STX6, CFTR, ADRB2, ELAVL1, DLG1, Protein Size: 246
Molecular Weight
27 kDa
Gene ID
51257
NCBI Accession
NM_016496 , NP_057580
UniProt
Q9P0N8
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